Male newborns and female newborns without ambiguous genitalia often escape detection until the baby experiences “adrenal crisis” from low production of cortisol - a life-threatening condition that can include dehydration, vomiting, low blood pressure, high fever and shock. Both boys and girls with congenital adrenal hyperplasia generally also have short stature.Ĭongenital adrenal hyperplasia is most easily identifiable in female infants born with ambiguous genitalia. While boys can appear to enter puberty at a very young age, girls can take on male characteristics and have ambiguous genitalia. The absence of cortisol and aldosterone hormones causes the body to produce androgen, a male sex hormone that can result in a number of changes in both boys and girls. At the Michigan Center for Congenital Adrenal Hyperplasia, part of the Pediatric Endocrinology, Diabetes and Metabolism Service at Michigan Medicine, our multidisciplinary team of specialists offers comprehensive evaluation and treatment of these disorders, and serves as a resource for congenital adrenal hyperplasia health care providers in Michigan. Children with congenital adrenal hyperplasia are unable to produce sufficient amounts of the hormones cortisol and aldosterone, and can experience issues from mild to life threatening. Congenital adrenal hyperplasia is a group of genetic disorders affecting the adrenal glands.
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